Blocking leukotrienes optimize asthma control: The BLOC survey
نویسندگان
چکیده
منابع مشابه
The Role of Leukotrienes in Respiratory Tract and Asthma
Polyunsaturated fatty acids play a role as precursors of biologically active compounds that can act as mediators or modulators of various cell functions. Thus three main groups of derivatives the prostaglandins, the thromboxanes, and recently discovered leukotrienes are formed by oxygenation and further transformation of various polyunsaturated fatty acids of which arachidonic acid plays t...
متن کاملLeukotrienes in the pathogenesis of asthma.
Asthma is a chronic inflammatory disease that is associated with widespread but variable airflow obstruction. The mechanisms that lead to airflow obstruction in asthma are bronchoconstriction, mucosal edema, increased secretion of mucus, and an inflammatory-cell infiltrate that is rich in eosinophils. Leukotrienes (LTs) B4, C4, D4, and E4 have been shown experimentally to play a role in each of...
متن کاملAsthma control in the Portuguese National Asthma Survey.
INTRODUCTION We aimed (1) to measure asthma control using a structure-questionnaire and patient self-perception of asthma-control in the Portuguese National Asthma Survey (INAsma) and (2) to study the relationship between asthma control and asthma-related quality of life. METHODS We analyze data of asthma patients from a cross-sectional, nationwide telephone interview study - INAsma. Controll...
متن کاملAdipokines and Cysteinyl Leukotrienes in the Pathogenesis of Asthma
Background. The prevalence of obesity has increased dramatically over the last decades, and its association with asthma is being increasingly recognized. Aims. Our hypothesis is that increased leptin and decreased adiponectin levels in obese subjects play a direct role in regulating inflammation in asthmatics. We wanted to examine the hypothesis that cysteinyl leukotrienes (cys-LT), inflammator...
متن کاملLeukotrienes and the other airway: Celiac disease and asthma collide
ON THE COVER Calderon et al. show that the pancreas has the unique feature of having macrophages from different lineages in distinct anatomical sites. The cover image illustrates that pancreatic islet macrophages derive from defi nitive hematopoiesis (orange), whereas stromal macrophages are of mixed origin, deriving from both defi nitive (orange) and primitive (green) hematopoiesis. Artwork by...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Annals of Thoracic Medicine
سال: 2007
ISSN: 1817-1737
DOI: 10.4103/1817-1737.33696